Iraq: Tackling multidrug-resistant tuberculosis, one patient at a time
Fatin is suffering from Multidrug-Resistant Tuberculosis (DR-TB) since nine months after being diagnosed at Baghdad’s National Tuberculosis Institute. She is taking the new oral treatment since then, and only has seven to eight months left of treatment before being considered fully cured. Iraq, 2021. © Chloe Sharrock
In the neighbourhood of Sadr City, in Baghdad, Iraq, Ihsan Ali sits with his four children in their home. The 44-year-old man is enjoying the company of his family after weeks of having to isolate from them. Ihsan has had tuberculosis (TB) couple of times before, but most recently he was diagnosed with a multidrug-resistant form of the disease.
Patients with TB generally experience serious symptoms which greatly affect their lives, including severe coughing, chest pain, significant weakness, sudden loss of weight and fever. Uncomplicated TB is curable, but patients must endure long months of treatment with harsh drugs. TB can also become resistant to these medications and evolve into a form of the disease called multidrug-resistant tuberculosis (MDR-TB).
Drug resistance emerges when TB medicines are used inappropriately, through incorrect prescription by healthcare providers, when poor quality drugs are used, and/or when patients do not adhere to their prescribed treatments. Until recently, the only way to treat MDR-TB was with potent oral and injectable drugs. This treatment regimen could take up to two years and could cause serious side effects such as deafness, kidney damage and severe psychological illness.
Rawabi, 37, is a patient being treated at the National Tuberculosis Institute. After being diagnosed with MDR-TB in 2019, Rawabi has been taking the new oral treatment since 2019, and is now considered as non contagious and is on the way to remission. © Chloe Sharrock
A better treatment for MDR-TB patients
In Iraq, Doctors Without Borders supports the Iraqi National Tuberculosis Institute to detect and diagnose TB and MDR-TB.
Doctors Without Borders has also introduced an innovative treatment regimen for MDR-TB patients, involving the use of new drugs bedaquiline and delamanid. This new, World Health Organization-recommended regimen involves all-oral drugs, removing the need for painful injections, which MDR-TB patients had to experience previously. These new drugs have also demonstrated superior patient adherence rates, higher success in treating MDR-TB in a shorter period and less side effects for patients.
During my previous infections, I was treated with daily injectable medications, which were giving me many side effects. My body was itching a lot and I had developed bruise marks on my skin. But since I started taking oral tablets, I feel better. The tablets still hurt my stomach, but they were far better and I have fewer side effects compared to the injections.Hameeda, a patient cured from MDR-TB
Hameeda, 65, photographed in her home, is Iraq’s first patient to be cured with the new oral treatment for multidrug-resistant tuberculosis. Before starting this treatment, she was having daily painful injections that had the potential of causing serious side effects; like hearing loss and kidney damage. Iraq, 2021. © MSF/CHLOE SHARROCK
“We are very happy that six Iraqi patients with MDR-TB have now fully completed their treatment and are cured. And as of August, 2021, we have 93 patients still being treated,” says Hemant Pangtey, Doctors Without Borders’ Project Medical Advisor in Baghdad who oversees the MDR-TB patient cohort.
Doctors Without Borders started implementing this new drug regimen to treat MDR-TB patients in Iraq in 2020, in partnership with the National Tuberculosis Institute. Later that year, it was officially recognised as the treatment regimen for all MDR-TB patients in the country. Today, all new patients diagnosed with MDR-TB in the country are treated with the oral new regimen , with only few exceptions based on medical requirements.
When I was told that I had a multidrug-resistant form of TB, doctors at the National Tuberculosis Institute told me about this new drug regimen that needs to be taken orally. I agreed straight away as I didn’t want to take painful injections again every day. I’ve been on this drug regimen for almost 10 months and I’m doing very well. The pills that I am taking are a blessing compared to the injections.Ihsan, an MDR-TB patient
Ihsan, a multidrug-resistant (MDR-TB) patient, posing with his family. Since February 2021, Ihsan was declared not contagious, and since then, he doesn't have to isolate himself anymore from his family. Iraq, 2021. © MSF/CHLOE SHARROCK
Alleviating the daily suffering
Patients with all forms of TB face many challenges in their personal lives due to their medical condition. In the early phase of the disease, they are infectious and must isolate themselves to avoid infecting others, which usually affects their mental health as well as their livelihood.
“Before getting sick, I used to work as a porter, but due to my illness I can’t work anymore. We can’t afford many things,” says Ibrahim Mohammed, a father of eight from the Baghdad suburb of Sadr City. He has MDR-TB and is currently in the infectious stage of the disease. “Most of the time, we can only afford food, and that’s mainly from my son’s work—he is a porter too.”
Doctors Without Borders provides support to patients with MDR-TB to decrease the financial burden of treatment, and to encourage people to attend their follow-up appointments as advised by their healthcare providers. This includes providing transportation allowances to and from the National Tuberculosis Institute, as well as food baskets for those who, like Ibrahim, are unable to work while sick. But our teams are aiming to go a step further in our projects for MDR-TB patients in Iraq.
The ongoing aim now is to decentralise the treatment so that people do not have to travel to Baghdad to benefit from it. Until now, patients from all over Iraq have had to come here to get their medications and follow-up care. We want this to change. Overcoming TB is hard and painful enough in itself. Suffering from The multidrug-resistant form of the disease is even more complicated to treat. So, we want to make the treatment process easier for patients in whatever way we can, and we have already, along with the National Tuberculosis Institute, taken big steps in this direction.”Hemant Pangtey, Project Medical Advisor
Since June 2021, Doctors Without Borders team has joined hands with NTP and International Organization for Migration (IOM) to provide trainings to healthcare providers in several governorates of Iraq on MDR-TB early detection, treatment and follow up care. “This decentralisation will help patients save time and money, by enabling them to access quality care closer to their homes,” concludes Pangtey. “We hope that all these steps will help to alleviate their suffering and contribute positively to both their treatment and their daily lives.”